Volume 20, Issue 4 (1-2025)                   J Health Syst Res 2025, 20(4): 308-324 | Back to browse issues page

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Karimi-Zeverdegani S, Azadian S, Harirsaz M. Introduction to the Stir Bar Sorptive Extraction Method and its Applications in Occupational Toxicology. J Health Syst Res 2025; 20 (4) :308-324
URL: http://hsr.mui.ac.ir/article-1-1541-en.html
1- Associate Professor, Department of Occupational Health and Safety Engineering, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran
2- PhD Student, Student Research Committee AND Department of Occupational Health and Safety Engineering, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran
3- MSc Student, Department of Technical Engineering, Daneshpajoohan Pishro Higher Education Institute, Isfahan, Iran
Abstract:   (724 Views)
Sample preparation is a crucial step in chemical analysis. Stir Bar Sorptive Extraction (SBSE) is one of the sample preparation methods employed in this field. This article provides an overview of the SBSE method and reviews its applications in toxicology. It discusses the extraction mechanism, factors influencing extraction efficiency, advantages, and disadvantages, and various applications of this method in pesticides, environmental cases, pharmaceuticals, food samples, forensic medicine, and more. The SBSE is an attractive alternative to traditional extraction methods, as it reduces solvent consumption, desorption costs, and extraction time. Its advantages include operational simplicity, good reproducibility, high recovery rates, and minimal use of organic solvents. In this review, 52 articles were selected for final analysis, with a portion of the results focusing on biological samples relevant to occupational toxicology. It can be concluded that this method is still in the early stages of widespread application, and many issues require further research.
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Type of Study: Research | Subject: Occupational health engineering and occupational safety
Received: 2023/04/25 | Accepted: 2023/10/1 | Published: 2025/01/4

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