fa مقایسه فراوانی و شدت ابتلا به عفونت کووید 19 قبل و بعد از انجام واکسیناسیون: یک مطالعه مقطعی در مراقبان بهداشتی بیمارستان کودکان امیرکلا آموزش بهداشت و ارتقاء سلامت education health and promotion پژوهشي Research <div style="text-align: justify;"><span style="line-height:115%"><span style="direction:rtl"><span style="unicode-bidi:embed"><b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">مقدمه: </span></span></span></b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">واکسیناسیون، بهترین رویکرد برای مبارزه با ویروس‌ها می‌باشد</span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">. پژوهش حاضر با هدف مقایسه فراوانی و شدت عفونت کووید 19 قبل و بعد از انجام </span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">واکسیناسیون</span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:"> در کارکنان و دستیاران بیمارستان کودکان بابل انجام شد.</span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:115%"><span style="font-family:"Times New Roman","serif""></span></span></span></span></span></span><br> <span style="line-height:115%"><span style="direction:rtl"><span style="unicode-bidi:embed"><b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">روش‌ها: </span></span></span></b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">این<b> </b></span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">مطالعه به صورت مقطعی و به روش سرشماری بر روی </span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">کارکنان و دستیاران </span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">بیمارستان کودکان بابل از </span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">اسفند سال </span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">1398</span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:"> تا </span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">۱۴۰۰</span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:"> انجام شد. </span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">تشخیص عفونت کووید 19 با مثبت شدن آزمایش </span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">Reverse transcription-polymerase chain reaction</span></span></span><span style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:"> (</span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">RT-PCR</span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">) قطعی می‌‌گردید. بر </span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">طبق دستورالعمل کشوری، سه دز </span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">واکسیناسیون علیه عفونت کووید 19، </span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">در صورت تمایل برای کارکنان انجام می‌شد. </span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">سپس فراوانی ابتلا و شدت بیماری کووید 19 ر قبل و بعد از واکسیناسیون مورد ارزیابی قرار گرفت. 05/0 > </span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">P</span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:"> به عنوان سطح معنی‌داری در نظر گرفته شد.</span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:115%"><span style="font-family:"Times New Roman","serif""></span></span></span></span></span></span><br> <span style="line-height:115%"><span style="direction:rtl"><span style="unicode-bidi:embed"><b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">یافته‌ها: </span></span></span></b><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">از مجموع </span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">371 </span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">نفر کارکنان و دستیاران</span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">،</span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:"> 84 نفر (76/19 درصد) در طی مدت تحقیق به عفونت کووید 19 مبتلا شدند که میانگین سنی آنان 33/9 </span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span cambria="" style="font-family:">&plusmn;</span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:"> 06/40 سال بود. فراوانی<span style="background:white"> ابتلا </span></span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">به </span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">عفونت<span style="background:white"> کووید 19 قبل از انجام واکسیناسیون، 9/69 درصد و بعد از دریافت دزهای اول، دوم و سوم واکسن به ترتیب 1/30، 5/21 و 3/11 درصد بود.</span></span></span></span> <span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">تفاوت معنی‌داری در شدت بیماری قبل و بعد از واکسیناسیون نوبت اول (001/0 > </span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">P</span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">) و دوم (</span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">043/0</span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:"> = </span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">P</span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">) مشاهده شد، اما تفاوت معنی‌داری در شدت بیماری قبل و بعد از واکسیناسیون نوبت سوم وجود نداشت (523/0 = </span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">P</span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">). </span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span style="font-family:"B Mitra""></span></span></span></span></span></span><br> <b><span dir="RTL" lang="AR-SA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" mitra="" style="font-family:">نتیجه‌گیری: </span></span></span></b><span dir="RTL" lang="AR-SA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" mitra="" style="font-family:">میزان ابتلا و شدت عفونت کووید 19 بعد از دریافت واکسن کاهش یافت. بنابراین، انجام واکسیناسیون طبق دستورالعمل‌های استاندارد در</span></span></span><span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" mitra="" style="font-family:"> کارکنان </span></span></span><span dir="RTL" lang="AR-SA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" mitra="" style="font-family:">مراقبت‌های بهداشتی توصیه می‌شود. </span></span></span><span style="line-height:115%"><span style="tab-stops:45.8pt 91.6pt 137.4pt 183.2pt 229.0pt 274.8pt 320.6pt 366.4pt 412.2pt 458.0pt 503.8pt 549.6pt 595.4pt 641.2pt 687.0pt 732.8pt"><span style="direction:rtl"><span style="unicode-bidi:embed"><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:"> </span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:115%"><span style="font-family:"Times New Roman","serif""></span></span></span></span></span></span></span></div> <div style="text-align: justify;"><span style="font-size:12pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:10.0pt"><span style="line-height:115%">Background:</span></span></b><span style="font-size:10.0pt"><span style="line-height:115%"> Vaccination is the most effective approach to combat viruses. The aim of this study was to compare the frequency and severity of coronavirus disease 2019 (COVID-19) infections among healthcare workers at Amirkola Children&#39;s Hospital, Babol, Iran, before and after vaccination.</span></span> <b><span style="font-size:10.0pt"><span style="line-height:115%"></span></span></b></span></span></span><br> <span style="font-size:12pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:10.0pt"><span style="line-height:115%">Methods</span></span></b><span style="font-size:10.0pt"><span style="line-height:115%">: The study was conducted cross-sectionally through census method on healthcare workers at a children&#39;s hospital in Babol, from March 2020 to 2022. The diagnosis of COVID-19 infection was confirmed when the reverse transcription-polymerase chain reaction (RT-PCR) test was positive.</span></span> <span style="font-size:10.0pt"><span style="line-height:115%">According to national guidelines, employees were offered three doses of COVID-19 vaccination. This study measured the frequency and severity of COVID-19 infection before and after vaccination. The significance level was set at P < 0.05. &nbsp;</span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span sans-serif="" style="font-family:Calibri,"><b><span style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">Findings:&nbsp;</span></span></b></span></span></span><span style="font-size:11pt"><span style="line-height:normal"><span sans-serif="" style="font-family:Calibri,"><span style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">Out of a total of 371 healthcare workers, 84 individuals (19.76%) were infected with COVID-19 during the study, with an average age of 40.06 &plusmn; 9.33 years. The frequency of COVID-19 infection was 69.9% before vaccination, and after receiving the first, second, and third doses of the corona vaccine, it was 30.1%, 21.5%, and </span></span><span style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">11.3%, respectively. There</span></span><span style="font-size:10.0pt"><span new="" roman="" style="font-family:" times=""> was a significant difference in the severity of the disease before and after the first (P < 0.001) and second (P = 0.043) vaccinations. However, there was no significant difference in the severity of the disease before and after the third round of vaccination (P = 0.523).</span></span><span style="font-size:12.0pt"><span style="font-family:"Times New Roman","serif""></span></span></span></span></span><br> <b><span style="font-size:10.0pt"><span style="line-height:107%"><span new="" roman="" style="font-family:" times="">Conclusion:</span></span></span></b><span style="font-size:10.0pt"><span style="line-height:107%"><span new="" roman="" style="font-family:" times=""> Based on the results of the present study, the infection rate and severity of COVID-19 decreased after receiving the coronavirus vaccine. Therefore, vaccination according to standard instructions is recommended for healthcare workers.</span></span></span></div> کووید 19, واکسن‌ها, مراقبان بهداشتی COVID-19, Vaccines, Health personnel 205 211 http://hsr.mui.ac.ir/browse.php?a_code=A-10-635-1&slc_lang=fa&sid=1 Somayeh Hasanpour سمیه حسن‌پور som.hassanpour@gmail.com 100319475328460022868 100319475328460022868 Yes Clinical Research Development Unit, Amirkola Children's Hospital, Babol University of Medical Sciences, Babol, Iran کارشناس ارشد، واحد توسعه تحقیقات بالینی، بیمارستان کودکان امیرکلا، دانشگاه علوم پزشکی بابل، بابل، ایران Maryam Nikpour مریم نیک‌پور maryamnikpour19@yahoo.com 100319475328460022869 100319475328460022869 No Assistant Professor, Non-Communicable Pediatric Diseases Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran استادیار، مرکز تحقیقات بیماری‌های غیر واگیر کودکان، پژوهشکده سلامت، دانشگاه علوم پزشکی بابل، بابل، ایران Faeze Aghajanpour فائزه آقاجانپور faezeaghajanpour@yahoo.com 100319475328460022870 100319475328460022870 No MSc Student, Student Research Committee, Babol University of Medical Sciences, Babol, Iran دانشجوی کارشناسی ارشد، کمیته تحقیقات دانشجویی، دانشگاه علوم پزشکی بابل، بابل، ایران Shahrbano Gorgineghad شهربانو گرجی‌نژاد sh.gorji2738@gmail.com 100319475328460022871 100319475328460022871 No Researcher, Clinical Research Development Unit, Amirkola Children's Hospital, Babol University of Medical Sciences, Babol, Iran پژوهشگر، واحد توسعه تحقیقات بالینی، بیمارستان کودکان امیرکلا، دانشگاه علوم پزشکی بابل، بابل، ایران Mohsen Mohammadi محسن محمدی dr.mohamadi61@yahoo.com 100319475328460022872 100319475328460022872 No Associate Professor, Non-Communicable Pediatric Diseases Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran دانشیار، مرکز تحقیقات بیماری‌های غیر واگیر کودکان، پژوهشکده سلامت، دانشگاه علوم پزشکی بابل، بابل، ایران