Volume 14, Issue 2 (7-2018)                   HSR 2018, 14(2): 165-170 | Back to browse issues page

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Barari A, Amini S, Abbassi-Dalooii A, Danekar G. The Effect of Eight Weeks of Combined Running and Swimming Training on Serotonin, Brain-Derived Neurotrophic Factor, and N-Methyl-D-Aspartate in Young Girls. HSR 2018; 14 (2) :165-170
URL: http://hsr.mui.ac.ir/article-1-1027-en.html
1- Associate Professor, Department of Sport Physiology, School of Physical Education , Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran
2- PhD Candidate, Student Research Committee AND Department of Nutrition, School of Paramedicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
3- Assistant Professor, Department of Sport Physiology, School of Physical Education, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran
4- MSc Student, Department of Sport Physiology, School of Physical Education, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran
Abstract:   (802 Views)
Background: Physical activity may help relieve some symptoms of mental disorders such as depression. The purpose of this study was to investigate the effect of eight weeks of combined training of running and swimming on N-Methyl-D-Aspartate (NMDA), Brain-Derived Neurotrophic Factor (BDNF), and serotonin in young girls.Methods: This quasi-experimental study was conducted with pre-test and post-test design with a control group. 20 young women (mean age: 24.20 ± 3.27 years, mean height: 1.61 ± 0.05 m, and mean weight: 56.24 ± 11.69 kg) were randomly assigned to 2 groups of experimental and control. Exercise schedule of subjects included a combination of running and swimming for eight weeks (three sessions per week). Running exercise included a 10-minute warm-up and 25 minutes of continuous running in the range of 60% to 75% maximum heart rate and 25 minutes of swimming. Before and after the training period, plasma levels of NMDA, BDNF, and serotonin were measured. To evaluate the normal distribution of data, Kolmogorov-Smirnov test (K-S test) and for between-groups comparison repeated measures analysis of variance (ANOVA) were used.Findings: In the experimental group, a significant increase in serotonin, BDNF, and NMDA levels was observed. The trend of change in body fat percentage in the experimental group showed a significant decrease compared with the control group. The trend of weight change had a significant decrease in the experimental group, but compared with the control group, no significant difference was observed.Conclusion: Endurance training increases the levels of serotonin, NMDA, and BDNF, and decreases the weight and body fat percentage, which will reduce the risk of depression, eventually. Moreover, it is possible that BDNF upregulates the expression of NMDA receptors.
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Type of Study: Research | Subject: education health and promotion
Received: 2020/07/16 | Accepted: 2018/07/15 | Published: 2018/07/15

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