Mendeley  

Zotero  

Mohammadi-Dashtaki N, Hosseinpour M, Maracy M R. The Incidence and Factors Associated with Major Congenital Malformations Recorded in Newborns Born in Chaharmahal and Bakhtiari Province, Iran, in 2016. HSR 2021; 16 (4) :257-264
URL: http://hsr.mui.ac.ir/article-1-1219-en.html

Background: Congenital malformations are one of the causes of infants’ disability and death. This study was performed to determine the incidence of major congenital anomalies and their relationship with some related factors at birth.
Methods: In this cross-sectional study, all newborns born in hospitals of Chaharmahal and Bakhtiari Province, Iran, were evaluated for major congenital malformations at birth. Information recorded in the case file including parent and infant characteristics was extracted from the Iranian Maternal and Neonatal Network (IMaN). Data were analyzed using generalized linear model (poisson regression).
Findings: Of 19666 newborns studied, 63 (3.2 per 1000) had major congenital malformations at birth. In the crude model, pregnancy age, neonatal birth weight, neonatal height, and neonatal head circumference variables were significantly associated with congenital malformations. In adjusted model 1, residence was significantly related to the incidence of congenital malformations and in adjusted model 2, the incidence of congenital malformations was related to neonatal pregnancy age, neonatal birth weight, and neonatal head circumference.
Conclusion: In some congenital malformations, disability can be prevented by early diagnosis and treatment. Therefore, the emphasis on public education to consider appropriate gestational age, proper nutrition before and during pregnancy, and emphasis on pre-pregnancy and during pregnancy care is necessary to prevent congenital anomalies.