Volume 22, Issue 3 (10-2026)
J Health Syst Res 2026, 22(3): 431-440 |
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Research code: 1404133
Ethics code: IR.MUI.PHANUT.REC.1404.102
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Ghadimi-Yari M, Aziznia S, Aziznia H. Investigation of the Antioxidant, Mechanical, and Antibacterial Properties of Hydroxypropyl Methylcellulose Films Containing Pomegranate Peel Extracts Obtained Using Different Solvents. J Health Syst Res 2026; 22 (3) :431-440
URL: http://hsr.mui.ac.ir/article-1-2098-en.html
URL: http://hsr.mui.ac.ir/article-1-2098-en.html
1- PhD Candidate, Nutrition and Food Security Research Center AND Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran
2- Assistant Professor, Department of Food Science and Hygiene, School of Veterinary Science, Ilam University, Ilam, Iran
3- PhD, Department of Food Biotechnology AND Research Institute of Food Science and Technology, Mashhad, Iran
2- Assistant Professor, Department of Food Science and Hygiene, School of Veterinary Science, Ilam University, Ilam, Iran
3- PhD, Department of Food Biotechnology AND Research Institute of Food Science and Technology, Mashhad, Iran
Abstract: (204 Views)
Background: Food packaging incorporating natural bioactive compounds offers a novel approach to environmental preservation and the extension of food shelf life. This study aimed to investigate the effect of different extraction solvents (water, methanol, and ethanol) on the total phenolic content and antioxidant activity of pomegranate peel extract. Subsequently, an active film based on hydroxypropyl methylcellulose (HPMC) was developed and evaluated.
Methods: The total phenolic content of the extracts was determined using the Folin–Ciocalteu method, and antioxidant activity was evaluated via the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay. The oxidative stability of soybean oil packaged with HPMC films containing three concentrations of the extracts (200, 400, and 600 ppm) was assessed over 60 days by measuring the peroxide value. Furthermore, mechanical properties were analyzed using tensile testing, and antibacterial activity against Staphylococcus aureus, Salmonella typhimurium, and Escherichia coli was examined using the disc diffusion method. Data were analyzed via analysis of variance (ANOVA) followed by Duncan's multiple range test (P < 0.05).
Findings: The methanolic extract exhibited the highest total phenolic content and antioxidant activity compared to the ethanolic and aqueous extracts. The film containing the methanolic extract demonstrated the greatest improvement in the oxidative stability of soybean oil, with the efficacy of the films in slowing oxidation increasing over time. Additionally, these films were the most effective treatment in inhibiting bacterial growth, particularly against Staphylococcus aureus. The incorporation of the extracts generally enhanced the flexibility of the HPMC films.
Conclusion: The HPMC films containing methanolic pomegranate peel extract, serving as active packaging with antioxidant and antimicrobial properties, hold significant potential for application in the food industry.
Methods: The total phenolic content of the extracts was determined using the Folin–Ciocalteu method, and antioxidant activity was evaluated via the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay. The oxidative stability of soybean oil packaged with HPMC films containing three concentrations of the extracts (200, 400, and 600 ppm) was assessed over 60 days by measuring the peroxide value. Furthermore, mechanical properties were analyzed using tensile testing, and antibacterial activity against Staphylococcus aureus, Salmonella typhimurium, and Escherichia coli was examined using the disc diffusion method. Data were analyzed via analysis of variance (ANOVA) followed by Duncan's multiple range test (P < 0.05).
Findings: The methanolic extract exhibited the highest total phenolic content and antioxidant activity compared to the ethanolic and aqueous extracts. The film containing the methanolic extract demonstrated the greatest improvement in the oxidative stability of soybean oil, with the efficacy of the films in slowing oxidation increasing over time. Additionally, these films were the most effective treatment in inhibiting bacterial growth, particularly against Staphylococcus aureus. The incorporation of the extracts generally enhanced the flexibility of the HPMC films.
Conclusion: The HPMC films containing methanolic pomegranate peel extract, serving as active packaging with antioxidant and antimicrobial properties, hold significant potential for application in the food industry.
Keywords: Edible film, Pomegranate peel extract, Hydroxypropyl methylcellulose, Antioxidant activity, Phenolic compounds, Antimicrobial activity
Type of Study: Research |
Subject:
Nutrition sciences and food industry
Received: 2025/06/29 | Accepted: 2026/03/14 | Published: 2026/10/7
Received: 2025/06/29 | Accepted: 2026/03/14 | Published: 2026/10/7
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