1- MSc Student, Student Research Committee, Food Security Research Center, Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran
2- Associate Professor, Food Security Research Center,Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran (Corresponding Author) Email: azadbakht@hlth.mui.ac.ir
Abstract: (762 Views)
Background: Omega-3 fatty acids have established beneficial effects for cardiovascular disease. The use of omega-3 supplements for patients with non-alcoholic fatty liver disease (NAFLD) was proposed. The purpose of this study was to review the relationship between omega-3 fatty acids intake and NAFLD. Methods: In this study, the terms such as NAFLD, omega-3 fatty acids, docosahexanoic acid, and eicosapentanoic acid were searched in PubMed search engine. 15 studies on NAFLD and omega-3 were found. Four of these studies were not fully available. Three studies were not strong in terms of design. Therefore, 8 studies were chosen. Findings: The results showed that omega-3 is a regulator of gene expression in the liver. Human studies have established that consumption of omega-3 have a role in reducing the hepatic steatosis, improving insulin sensitivity and decrease the inflammatory marker. More clinical trials should be conducted to confirm these findings. Conclusion: Omega-3 fatty acids may improve symptoms associated with NAFLD, but more studies should be done in this area.
Type of Study:
Research |
Subject:
education health and promotion Received: 2020/07/16 | Accepted: 2013/06/15 | Published: 2013/06/15