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Background: The negative side effects of infertility affect not only the relations between the couple but also other aspects of their lives and destroy their personal, social, and professional functions. This research aims to study the social consequences of infertility on families in the city of Isfahan. Sociological and psychological theories provide the theoretical framework of the study.Methods: The research method was survey and the data collection tool was questionnaire. The research was conducted on 384 infertile women chosen by simple random sampling from among those going to Isfahan fertility and infertility center. The research instrument had face validity and to test its validity, Cronbach Alpha coefficient was used. These data were analyzed by Chi Square, Spearman and Pearson correlation coefficient.Findings: Research results showed a statistically significant relationship between duration of infertility and mental disorders (χ 2 = 15.896 , p< 0.05) marital conflicts (χ 2 = 21.322 , p< 0.05) , divorce possibility (χ 2 = 38.831 , p< 0.05) and a decline in social relations (χ 2 = 26.857 , p< 0.05) . There also existed a significant relationship between mental disorders and the level of education (r=-0.151, p< 0.05) and religiousness (χ 2 =18.345 , p< 0.05) of these infertile women. Research findings, on the other hand, showed no significant relationship between infertile women’s mental disorders, age (r =0.014, p< 0.05), occupation (r =0.025, p< 0.05) and place of residence (r = 0.065, p< 0.05).Conclusion: The results showed that infertile women, as compared with fertile ones, have considerably more psychological problems and that this issue can negatively affect their marital life and social relations.

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