Volume 13, Issue 4 (1-2018)
J Health Syst Res 2018, 13(4): 429-435 |
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Khosravi Z S, Kafeshani M, Hassanzadeh A, Tavasoli P, Entezari M H. Effect of Vitamin D Supplementation on Weight Loss, Glycemic Indices, and Lipid Profile in Obese and Overweight Women: A Clinical Trial Study. J Health Syst Res 2018; 13 (4) :429-435
URL: http://hsr.mui.ac.ir/article-1-982-en.html
URL: http://hsr.mui.ac.ir/article-1-982-en.html
Zahra Sadat Khosravi1 
, Marzieh Kafeshani1 , Akbar Hassanzadeh2 , Parastoo Tavasoli1 , Mohammad Hassan Entezari3
, Marzieh Kafeshani1 , Akbar Hassanzadeh2 , Parastoo Tavasoli1 , Mohammad Hassan Entezari3
1- Food Security Research Center AND School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran
2- Lecturer, Department of Epidemiology and Biostatic, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran
3- Associate Professor, Food Security Research Center AND School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran
2- Lecturer, Department of Epidemiology and Biostatic, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran
3- Associate Professor, Food Security Research Center AND School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran
Abstract: (1271 Views)
Background: Vitamin D deficiency is considered as a public health problem throughout the world. The aim of this study was to evaluate the effect of vitamin D on weight loss, high-sensitivity C-reactive protein (hs_CRP), and insulin resistance in obese and overweight women.Methods: This double blind clinical trial was done on 53 overweight and obese women who divided into two groups. The intervention group received vitamin D supplements with doze of 50000 IU per week for 6 weeks and another received placebo. The anthropometric factors and biochemical markers were measured before and after intervention. Independent samples t and paired samples t test were used to compare the mean between and within groups, respectively.Findings: Serum vitamin D increased significantly compared to control group (P < 0.001); but other factors including anthropometric factors, hs_CRP, fasting blood sugar (FBS), and insulin resistance (IR) did not change significantly (P > 0.050 for all).Conclusion: The evidence of this study suggests that supplementation of vitamin D in obese and overweight women did not confirm the effect of vitamin D supplementation on anthropometrics, body mass index (BMI), hs_CRP, and insulin resistance.
Type of Study: Research |
Subject:
education health and promotion
Received: 2020/07/16 | Accepted: 2018/01/15 | Published: 2018/01/15
Received: 2020/07/16 | Accepted: 2018/01/15 | Published: 2018/01/15
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