Volume 20, Issue 3 (10-2024)
J Health Syst Res 2024, 20(3): 205-211 |
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Research code: 724134044
Ethics code: IR.MUBABOL.HRI.REC.1400.161
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Hasanpour S, Nikpour M, Aghajanpour F, Gorgineghad S, Mohammadi M. Comparison of Frequency and Severity of COVID-19 Infection before and after Vaccination: A Cross-Sectional Study in Healthcare Workers of Amirkola Children's Hospital, Iran. J Health Syst Res 2024; 20 (3) :205-211
URL: http://hsr.mui.ac.ir/article-1-1586-en.html
URL: http://hsr.mui.ac.ir/article-1-1586-en.html
Somayeh Hasanpour 
1, Maryam Nikpour2 , Faeze Aghajanpour3 , Shahrbano Gorgineghad4 , Mohsen Mohammadi5
1, Maryam Nikpour2 , Faeze Aghajanpour3 , Shahrbano Gorgineghad4 , Mohsen Mohammadi5
1- Clinical Research Development Unit, Amirkola Children's Hospital, Babol University of Medical Sciences, Babol, Iran
2- Assistant Professor, Non-Communicable Pediatric Diseases Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran
3- MSc Student, Student Research Committee, Babol University of Medical Sciences, Babol, Iran
4- Researcher, Clinical Research Development Unit, Amirkola Children's Hospital, Babol University of Medical Sciences, Babol, Iran
5- Associate Professor, Non-Communicable Pediatric Diseases Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran
2- Assistant Professor, Non-Communicable Pediatric Diseases Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran
3- MSc Student, Student Research Committee, Babol University of Medical Sciences, Babol, Iran
4- Researcher, Clinical Research Development Unit, Amirkola Children's Hospital, Babol University of Medical Sciences, Babol, Iran
5- Associate Professor, Non-Communicable Pediatric Diseases Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran
Abstract: (440 Views)
Background: Vaccination is the most effective approach to combat viruses. The aim of this study was to compare the frequency and severity of coronavirus disease 2019 (COVID-19) infections among healthcare workers at Amirkola Children's Hospital, Babol, Iran, before and after vaccination.
Methods: The study was conducted cross-sectionally through census method on healthcare workers at a children's hospital in Babol, from March 2020 to 2022. The diagnosis of COVID-19 infection was confirmed when the reverse transcription-polymerase chain reaction (RT-PCR) test was positive. According to national guidelines, employees were offered three doses of COVID-19 vaccination. This study measured the frequency and severity of COVID-19 infection before and after vaccination. The significance level was set at P < 0.05.
Findings: Out of a total of 371 healthcare workers, 84 individuals (19.76%) were infected with COVID-19 during the study, with an average age of 40.06 ± 9.33 years. The frequency of COVID-19 infection was 69.9% before vaccination, and after receiving the first, second, and third doses of the corona vaccine, it was 30.1%, 21.5%, and 11.3%, respectively. There was a significant difference in the severity of the disease before and after the first (P < 0.001) and second (P = 0.043) vaccinations. However, there was no significant difference in the severity of the disease before and after the third round of vaccination (P = 0.523).
Conclusion: Based on the results of the present study, the infection rate and severity of COVID-19 decreased after receiving the coronavirus vaccine. Therefore, vaccination according to standard instructions is recommended for healthcare workers.
Methods: The study was conducted cross-sectionally through census method on healthcare workers at a children's hospital in Babol, from March 2020 to 2022. The diagnosis of COVID-19 infection was confirmed when the reverse transcription-polymerase chain reaction (RT-PCR) test was positive. According to national guidelines, employees were offered three doses of COVID-19 vaccination. This study measured the frequency and severity of COVID-19 infection before and after vaccination. The significance level was set at P < 0.05.
Findings: Out of a total of 371 healthcare workers, 84 individuals (19.76%) were infected with COVID-19 during the study, with an average age of 40.06 ± 9.33 years. The frequency of COVID-19 infection was 69.9% before vaccination, and after receiving the first, second, and third doses of the corona vaccine, it was 30.1%, 21.5%, and 11.3%, respectively. There was a significant difference in the severity of the disease before and after the first (P < 0.001) and second (P = 0.043) vaccinations. However, there was no significant difference in the severity of the disease before and after the third round of vaccination (P = 0.523).
Conclusion: Based on the results of the present study, the infection rate and severity of COVID-19 decreased after receiving the coronavirus vaccine. Therefore, vaccination according to standard instructions is recommended for healthcare workers.
Type of Study: Research |
Subject:
education health and promotion
Received: 2023/06/25 | Accepted: 2024/03/12 | Published: 2024/10/6
Received: 2023/06/25 | Accepted: 2024/03/12 | Published: 2024/10/6
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