Volume 14, Issue 1 (4-2018)
J Health Syst Res 2018, 14(1): 68-72 |
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Mirrezaei M, Karimi Zeverdegani S, Rismanchian M, Hassanzadeh A. Investigating the Effect of Organophosphate Pesticides on Plasma Cholinesterase Activity among the Farmers. J Health Syst Res 2018; 14 (1) :68-72
URL: http://hsr.mui.ac.ir/article-1-1000-en.html
URL: http://hsr.mui.ac.ir/article-1-1000-en.html
1- MSc Student, Student Research Committee AND Department of Occupational Health Engineering, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran
2- Assistant Professor, Department of Occupational Health Engineering, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran
3- - Lecturer, Department of Biostatistics and Epidemiology, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran
2- Assistant Professor, Department of Occupational Health Engineering, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran
3- - Lecturer, Department of Biostatistics and Epidemiology, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran
Abstract: (1620 Views)
Background: Organophosphate compounds are a class of pesticides with well-known uses in agriculture. Poisoning with this group of toxins, has created major problems around the world, especially in developing countries. This study aimed to investigate the effect of organophosphate pesticides on plasma cholinesterase activity among the farmers.Methods: This cross-sectional study was done on 17 male spraying farmers, who were exposed to organophosphate pesticides, and 17 non-farmer people as controls. Before and after spraying operations, a blood sample was collected from each of the participants in both groups. Plasma cholinesterase activity was investigated using transparent-substrate (TS) technology model photometric device.Findings: The mean level of cholinesterase enzyme activity in the case group (farmers exposed to organophosphate pesticides) was 12086.2 mg/l before the spraying; which decreased to 8516.3 mg/l after spraying. The mean level of the activity of this enzyme in the control group was 13655.8 mg/l.Conclusion: Considering the importance of the evaluation of organophosphate contact among the farmers, and its effect on cholinesterase enzyme activity, it can be said that training farmers to produce organic products, to use less pesticide, and to prevent poisoning caused by spraying, seems to be necessary.
Type of Study: Research |
Subject:
education health and promotion
Received: 2020/07/16 | Accepted: 2018/04/15 | Published: 2018/04/15
Received: 2020/07/16 | Accepted: 2018/04/15 | Published: 2018/04/15
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