Volume 11, Issue 2 (6-2015)
J Health Syst Res 2015, 11(2): 317-326 |
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Paknahad Z, Ahmadivasmehjani A, Maracy M R. Association of Serum 25-hydroxyvitamin D concentration and Markers of Metabolic Syndrome in adult women. J Health Syst Res 2015; 11 (2) :317-326
URL: http://hsr.mui.ac.ir/article-1-778-en.html
URL: http://hsr.mui.ac.ir/article-1-778-en.html
1- Ph.D, Food Security Research Center, Isfahan University of Medical Sciences, Department of Clinical Nutrition, Faculty of Nutrition and Food Sciences, Isfahan, Iran and B.Sc, Department of Clinical Nutrition, Faculty of Nutrition and Food Sciences, Isfahan University of Medical Sciences, Isfahan, Iran
2- B.Sc, Department of Clinical Nutrition, Faculty of Nutrition and Food Sciences, Isfahan University of Medical Sciences, Isfahan, Iran
3- Ph.D, Department of Epidemiology and Biostatistics, Faculty of Health, Isfahan University of Medical Sciences, Isfahan, Iran
2- B.Sc, Department of Clinical Nutrition, Faculty of Nutrition and Food Sciences, Isfahan University of Medical Sciences, Isfahan, Iran
3- Ph.D, Department of Epidemiology and Biostatistics, Faculty of Health, Isfahan University of Medical Sciences, Isfahan, Iran
Abstract: (1090 Views)
Background: Association between vitamin D deficiency and some components of metabolic syndrome was previously investigated by some cross sectional studies. Howevr, these findings are usually inconsistent. With regard to the high prevalence of vitamin D deficiency in Iran, this study was conducted to investigate the association of Serum 25-hydroxyvitamin D concentration and markers of metabolic syndrome in adult womenMethods: In this cross sectional study, 156 women aged ≥30 havig at least three criteria of the metabolic syndrome were recruited by consecutive random sampling. Serum 25(OH) D levels and the components of the metabolic syndrome were measured. Metabolic syndrome was defined according to NCEP/ATP III criteria. Subjects were grouped in three chategories according to their serum concentrations of 25(OH)D.Findings: Mean concentration of 25-hydroxyvitamin D in serum was 20.5 ± 10.8 ng/ml. 54.5% of the subjects were identified vitamin D deficient. Also, 23.1% and 22.4% were found insufficient and sufficient, respectively. After adjustment for age, BMI and physical activity, ANCOVA showed fasting blood sugar concentration was inversely associated with serum 25(OH)D(P=0.004). There was a significant correlation between HDL-C and vitamin D status (P=0.014). Waist circumference showed a relative but not statistically significant correlation with serum vitamin D concentration. Moreover, no significant association was observed between any other components of metabolic syndrome and vitamin D level across the chategorized groups.Conclusion: Based on stong association between serum 25(OH) D level with fasting blood sugar and HDL-C concentration, the former can be a predicivte parameter for chronic disease. However, to determine the role of vitamin D in metabolic syndrome and related disease, large prospective studies and clinical trials should be conducted in the future.Key Words: Metabolic Syndrome, Diet, 25-hydroxyvitamin D, Blood Glucose, Lipid Profiles, Women
Type of Study: Research |
Subject:
education health and promotion
Received: 2020/07/16 | Accepted: 2015/06/15 | Published: 2015/06/15
Received: 2020/07/16 | Accepted: 2015/06/15 | Published: 2015/06/15
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